![T-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate (PB4) CAS NO.147489-06-3](/uploads/202224095/t-butyl-3r-5s-7-2-cyclopropyl-4-423061586456.png)
(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester Basic information
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Product Name: |
(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester |
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Synonyms: |
(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester;tert-Butyl(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate;(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluoro?phenyl)3-quinoline-base]-2,2-dimethyl-1,3-dioxane-6-heptene?acid?tert-butyl?ester;tert-butyl 2-((4R,6S);pitavastatin intermediate 3R5S isomer;2-[6-[2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetic acid tert-butyl ester;3-dioxane-6-heptene?acid?tert-butyl?ester;6E)-7-[2-cyclopropyl-4-(4-fluoro?phenyl)3-quinoline-base]-2 |
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CAS: |
147489-06-3 |
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MF: |
C32H36FNO4 |
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MW: |
517.63 |
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EINECS: |
1592732-453-0 |
(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester Chemical Properties
| Melting point | 105-116 °C(Solv: hexane (110-54-3)) |
| Boiling point | 604.6±55.0 °C(Predicted) |
| density | 1.184±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 4.61±0.50(Predicted) |
| form | Solid |
| color | White to Off-White |
(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester Usage And Synthesis
| Uses | t-Butyl (3R,5S)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate is an impurity from the synthesis of HMG-CoA reductase inhibitor Pitavastatin [P531040, (Z)-Pitavastatin Calcium Salt]. |
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![[2-Cyclopropyl-4-(4-fluorophenyl)-quinolin-3-ylmethyl]-triphenyl-phosphonium Bromido CAS NO.154057-58-6](/uploads/202224095/small/2-cyclopropyl-4-4-fluorophenyl-quinolin-312354620752.png)
