Anti Inflammatory Drugs

They have the effects of relieving fever, reducing pain, and suppressing inflammation. By inhibiting the activity of cyclooxygenase (COX), they reduce the synthesis of prostaglandins, thereby alleviating the inflammatory response. Examples include aspirin, ibuprofen, naproxen, etc. They are commonly used to relieve mild to moderate pain and various types of inflammation.

Also known as glucocorticoid drugs, they possess powerful anti-inflammatory and immunosuppressive effects. They can inhibit the inflammatory response from multiple aspects. For instance, prednisone, dexamethasone, etc. are often used for severe inflammation and autoimmune diseases. However, long-term use may have numerous side effects.

Disease-Modifying Antirheumatic Drugs (DMARDs), such as methotrexate, sulfasalazine, etc., can delay the progression of the disease. They are commonly used in the treatment of rheumatic diseases like rheumatoid arthritis, which can improve joint function and prevent joint destruction.

They are a new type of anti-inflammatory drugs. For example, tumor necrosis factor-α antagonists, interleukin-6 receptor antagonists, etc. They precisely inhibit inflammation by specifically acting on key cytokines or immune cells in the inflammatory process. They usually have good curative effects but are relatively expensive.

This category includes some natural drugs or their extracts with anti-inflammatory effects, such as tripterygium glycosides, as well as new small-molecule drugs like JAK inhibitors, such as tofacitinib. They exert anti-inflammatory effects through different mechanisms, providing more treatment options for inflammatory diseases.