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Bis(trimethylsilyl)trifluoroacetamide Basic information
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Product Name: |
Bis(trimethylsilyl)trifluoroacetamide (BSTFA) |
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Synonyms: |
BSTFA containing 1% TMCS;N,O-Bis(trimethylsily)trifluoroamide;N,O-bis(trimethylsilyl)acetamide,*with 10%;N,O-Bis(trimethylsilyl)trifluoroacetamide, contains 10% TMCS;N,O-Bis(trimethylsilyl)trifluoroacetamide, contains 1% TMCS, ampuled under argon;Bis(trimethylsilyl)trifluoroacetamide for gas chromatography;Acetamide, 2,2,2-trifluoro-O,N-bis(trimethylsilyl)-;Ethanimidic acid, 2,2,2-trifluoro-N-(trimethylsilyl)-, trimethylsilyl ester |
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CAS: |
25561-30-2 |
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MF: |
C8H18F3NOSi2 |
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MW: |
257.4 |
Bis(trimethylsilyl)trifluoroacetamide Physical and chemical properties
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Melting point |
-10°C |
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Boiling point |
45-50 °C14 mm Hg(lit.) |
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Density |
0.97 g/mL(lit.) |
| refractive index | n20/D 1.384(lit.) |
| Fp | 75℃ |
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Storage temp. |
2-8°C |
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Solubility |
Miscible with chloroform. |
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Form |
Liquid |
| pka | 1.82±0.50(Predicted) |
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Specific Gravity |
0.971 |
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Color |
Colorless to pale yellow |
| Sensitive | Moisture Sensitive |
| Water Solubility | hydrolyses |
Bis(trimethylsilyl)trifluoroacetamide Specification
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Usage |
To be used as a neutral silylation reagent in the silanization protection of amino groups, amino acids, phenols, carboxylic acids and enols. As a mild neutral silylation reagent, it not only has high reactivity and good selectivity, but also has a reaction yield. High rate, simple post-processing, etc. |
Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.
Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.
Dangerous goods category: Class 3 flammable liquid, Class 8 corrosive
Packing: 25KG UN plastic drum, 50KGUN steel-plastic composite drum
Generally used as pharmaceutical intermediates
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