Bis(trimethylsilyl)trifluoroacetamide Basic information
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Product Name:
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Bis(trimethylsilyl)trifluoroacetamide (BSTFA)
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Synonyms:
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BSTFA containing 1% TMCS;
N,O-Bis(trimethylsily)trifluoroamide;
N,O-bis(trimethylsilyl)acetamide,with10%;
N,O-Bis(trimethylsilyl)trifluoroacetamide, contains 10% TMCS;
N,O-Bis(trimethylsilyl)trifluoroacetamide, contains 1% TMCS, ampuled under argon;
Bis(trimethylsilyl)trifluoroacetamide for gas chromatography;
Acetamide, 2,2,2-trifluoro-O,N-bis(trimethylsilyl)-;
Ethanimidic acid, 2,2,2-trifluoro-N-(trimethylsilyl)-, trimethylsilyl ester
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CAS:
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25561-30-2
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MF:
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C8H18F3NOSi2
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MW:
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257.4
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Melting point
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-10°C
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Boiling point
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45-50 °C14 mm Hg(lit.)
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Density
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0.97 g/mL(lit.)
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refractive index
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n20/D 1.384(lit.)
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Fp
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75℃
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Storage temp.
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2-8°C
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Solubility
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Miscible with chloroform.
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Form
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Liquid
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pka
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1.82±0.50(Predicted)
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Specific Gravity
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0.971
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Color
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Colorless to pale yellow
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Sensitive
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Moisture Sensitive
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Water Solubility
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hydrolyses
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Bis(trimethylsilyl)trifluoroacetamide Specification
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Usage
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To be used as a neutral silylation reagent in the silanization protection of amino groups, amino acids, phenols, carboxylic acids and enols. As a mild neutral silylation reagent, it not only has high reactivity and good selectivity, but also has a reaction yield. High rate, simple post-processing, etc.
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Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.
Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.
Dangerous goods category: Class 3 flammable liquid, Class 8 corrosive
Packing: 25KG UN plastic drum, 50KGUN steel-plastic composite drum
Generally used as pharmaceutical intermediates
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