| Product Name: | D-Serine |
| Synonyms: | (R)-2-AMINO-3-HYDROXYPROPIONIC ACID; β-Hydroxyalanine; D-SERINE 98.5%; D-Serine,>99%; D-2-Amino-3-Hydroxypropionic; (2R)-2-amino-3-hydroxy-propanoic acid; D-Serin; (R)-2-amino-3-hydroxypropanoic acid |
| CAS: | 312-84-5 |
| MF: | C3H7NO3 |
| MW: | 105.09 |
| EINECS: | 206-229-4 |
D-Serine Chemical Properties
| Melting point | 220 °C |
| alpha | -14.75 º (c=10 2 N HCl) |
| Boiling point | 197.09°C (rough estimate) |
| density | 1.3895 (rough estimate) |
| refractive index | 1.4368 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | H2O: 0.1 g/mL, clear, colorless |
| pka | 2.16±0.10(Predicted) |
| form | Crystalline Powder |
| color | White |
| Water Solubility | 346 g/L (20 ºC) |
| Merck | 14,8460 |
| BRN | 1721403 |
| InChIKey | MTCFGRXMJLQNBG-UWTATZPHSA-N |
| LogP | -1.490 (est) |
D-Serine Usage And Synthesis
| Chemical Properties | D-serine is a off-white crystalline powder with a faint musty odor.It is an amino acid found in the brain. Derived from Glycine, d-serine is a neuromodulator, meaning it regulates the activities of neurons. |
| Uses |
A proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. Inhibitor of serine palmitoyltransferase. A neuromodulator. D-Serine is involved in the biosynthesis of purines, pyrimidines, and other amino acids. D-Serine also is an agonist of glycine site of the NMDA-type glutamate receptor. It also acts as Lacosamide intermediate. D-serine has been used as a substrate in D-amino acid oxidase (DAO) activity in human 1321N1 astrocytoma cells. It has also been used in intracerebroventricular administration in rat for the induction of antinociceptive effect. |
| Definition | D-serine is the R-enantiomer of serine. It has a role as a NMDA receptor agonist, a human metabolite and an Escherichia coli metabolite. It is a D-alpha-amino acid and a serine. It is a conjugate base of a D-serinium. It is a conjugate acid of a D-serinate. It is an enantiomer of a L-serine. It is a tautomer of a D-serine zwitterion. |
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