What are Avanafil intermediates?
An Avanafil intermediate is a key chemical intermediate used in the synthesis of Avanafil, a medication for treating erectile dysfunction (ED). Avanafil is a phosphodiesterase type 5 (PDE5) inhibitor that works by blocking the activity of the PDE5 enzyme, thereby enhancing the vasodilatory effect of nitric oxide (NO) in the penile corpus cavernosum. This improves blood flow, helping to achieve and maintain an erection.
Avanafil intermediates typically refer to core organic compounds that play a pivotal role in the synthetic pathway of Avanafil. These may include intermediates used to construct the pyrazolopyrimidinone core structure, precursors for introducing key functional groups (such as alkyl or amide groups), or intermediates used for stereochemical control (since Avanafil has specific stereoisomeric configurations). Through multiple chemical reactions-such as cyclization, substitution, and coupling-these intermediates are ultimately transformed into the final Avanafil product.
These intermediates serve as critical building blocks in the drug synthesis process. Their purity, structure, and reactivity directly influence the final quality, efficacy, and production cost of Avanafil, making them essential foundations in the research, development, and industrial production of the medication.
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2-AMINOMETHYLPYRIMIDINE HYDROCHLORIDE CAS NO.:372118-67-7CAS: 372118-67-7MF: C5H8ClN3MW: 145.59EINECS 692-058-4 -
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3-CHLORO-4-METHOXYBENZYLAMINE HYDROCHLORIDE CAS NO.:41965...CAS: 41965-95-1MF: C8H11Cl2NOMW: 208.09EINECS:609-972-6 -
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5-PyriMidinecarboxylic Acid,4-[[(3-chloro-4-Methoxyphenyl...CAS: 330785-83-6MF: C20H25ClN4O4MW: 420.89EINECS 809-849-9
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