What are Edoxaban Intermediates?
Edoxaban intermediates refer to the key chemical intermediates or precursor compounds used in the synthesis of the novel oral anticoagulant drug edoxaban (brand name: Savaysa/Lixiana). Edoxaban is a direct, highly selective Factor Xa inhibitor. By inhibiting the activity of coagulation Factor Xa, it reduces the production of thrombin, thereby effectively preventing and treating thrombotic diseases such as deep vein thrombosis (DVT), pulmonary embolism (PE), and for stroke prevention in patients with atrial fibrillation.
Edoxaban intermediates typically play a critical role in specific steps of the drug synthesis process, such as constructing its core pharmacophore (e.g., morpholinone or aromatic carboxylic acid structures), introducing chiral centers, or achieving selective functional group transformations. These intermediates are essential for controlling the efficiency, purity, and stereo-selectivity of the synthetic route. They serve as the foundation for ensuring the quality, efficacy, and safety of edoxaban, and hold significant importance in the research, development, and industrial production of anticoagulant drugs.
-
![CAS：365997-33-7 (1S,3R,4R)-3-(Boc-aMino)-4-hydroxy-cyclohexanecarboxylic Acid Ethyl Ester]()
CAS：365997-33-7 (1S,3R,4R)-3-(Boc-aMino)-4-hydroxy-cycloh...CAS No. 365997-33-7MF C14H25NO5MW 287.35 -
![Edoxaban Tosylate Monohydrate CAS NO.:1229194-11-9]()
Edoxaban Tosylate Monohydrate CAS NO.:1229194-11-9CAS: 1229194-11-9MF: C31H38ClN7O7S2MW: 720.26EINECS: 1592732-453-0 -
![Tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexylcarbaMateCAS NO.:365998-36-3]()
Tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cycloh...tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexylcarbaMate Usage -
![(1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one CAS NO.:139893-81-5]()
(1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one CAS NO....(1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one (1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one Usage -
![5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride CAS NO.:720720-96-7]()
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carb...CAS: 1243308-37-3MF: C9H10Cl2N2O3MW: 265.09EINECS: 860-082-6 -
![Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate Hydrochloride CAS NO.:1243308-37-3]()
Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate Hydroc...CAS: 1243308-37-3MF: C9H10Cl2N2O3MW: 265.09EINECS: 860-082-6 -
![Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate Oxalate CAS NO.:1210348-34-7]()
Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl...tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Usage
![(1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one CAS NO.:139893-81-5](/uploads/24095/small/cas-no-139893-81-5642d8.png?size=380x0)
![5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride CAS NO.:720720-96-7](/uploads/24095/small/cas-no-720720-96-7a6cc0.png?size=380x0)
![Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate Oxalate CAS NO.:1210348-34-7](/uploads/24095/small/tert-butyl-1r-2s-5s-2-amino-5-dimethylamino00702.png?size=380x0)
We're well-known as one of the leading edoxaban intermediates manufacturers and suppliers in China. Our factory offers high quality edoxaban intermediates made in China with competitive price. Welcome to contact us for wholesale service.
