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tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate
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Product Name:
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tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate
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Synonyms:
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Tert-Butyl(1R,2S,5S)-2-azido-5-[(diMethylaMino)carbonyl]cyclohexylcarbaMateoxalicacid;oxalicacidtert-butylN-[(1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexyl]carbaMate;(2-Azido-5-diMethylcarbaMoyl-cyclohexyl)-carbaMicacidtert-butylesteroxalicacid;EthanediaMideiChemicalbookMpurityA/EdoxabanIntermediateII;tert-butyl((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamateoxalicacid;Edoxaban-1;N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-Carbamicacid,1,1-dimethylethylester,ethanedioate(1:1);2EthanediaMideiMpurityA
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CAS:
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1210348-34-7
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MF:
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C16H29N3O7
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MW:
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375.42
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EINECS:
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1592732-453-0
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tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate
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Melting point
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182.5℃
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Solubility
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Soluble in DMSO (slightly) and methanol (slightly).
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Storage temp.
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Storage at room temperature
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Form
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solid
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Color
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White
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tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Usage
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Uses
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Edoxaban intermediate 2 is a key intermediate compound in the synthesis of the anticoagulant drug edoxaban, typically playing an important role during the construction of the drug's molecular skeleton or the formation of key pharmacophoric groups. This intermediate is generally used to introduce or transform core structural units of edoxaban (such as the morpholinone ring, aromatic carboxylic acid group, or chiral center), which are crucial for ensuring the target molecule's chemical structure, stereo-selectivity, and biological activity. It plays a vital role in optimizing the synthetic route, improving product purity and yield, and serves as an essential foundational intermediate to ensure the quality and efficacy of edoxaban. It is widely used in the research, development, and industrial production of anticoagulant drugs.
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