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Edoxaban tosylate monohydrate
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Product Name:
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Edoxaban tosylate monohydrate |
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Synonyms:
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Edoxaban(tosylateMonohydrate);Edoxabantosilate;Ethanediamide,N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-,4-methylbenzenesulfonate,hydrate;Edoxabanp-toluenesulfonatemonohydrate; N-(5-Chloropyridin-2-yl)-N'-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamidep-toluenesulfonatemonohydrate;edoxabantosylatehydrate; N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide4-methylbenzenesulfonatehydrate;EdoxabanTosylateHydrate1 |
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CAS:
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1229194-11-9
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MF:
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C31H38ClN7O7S2
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MW:
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720.26
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EINECS:
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1592732-453-0
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Melting point
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>252°C (dec.)
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Solubility
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Chloroform (slightly soluble), DMSO (slightly soluble), Methanol (slightly soluble, ultrasonic treatment) |
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Storage temp.
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Hygroscopic, Refrigerator, under inert atmosphere |
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Form
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solid
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Color
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White
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Uses
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Prevention of venous thromboembolism (VTE): Used in patients undergoing hip or knee replacement surgery to reduce the risk of postoperative deep vein thrombosis and pulmonary embolism; Treatment and prevention of stroke in non-valvular atrial fibrillation (NVAF): By selectively inhibiting Factor Xa, it reduces thrombus formation, thereby lowering the risk of stroke and systemic embolism in NVAF patients; Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE): Employed for the anticoagulant therapy of acute DVT or PE and to prevent recurrence of thrombosis. |
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