Salmeterol Basic Information

Product Name	Salmeterol
Synonyms	4-HYDROXY-A1-[ [ [6-(4-PHENYLBUTOXY) HEXYL] AMINO] METHYL ]-1, 3-BENZENEDIMETHANOL; 2-(hydroxymethyl)-4-[ 1-hydroxy-2-[ 6-(4-phenylbutoxy) hexylamino ] ethyl ]-phenol; SALMETEROL; (+-)-4-hydroxy-alpha1Chemicalbook-( ( ( 6-(4-phenylbutoxy) hexyl ) amino ) methyl)-1, 3-benzenedi; 1,3-benzenedimethanol, 4-hydroxy-alpha1-( ( (6-(4-phenylbutoxy) hexyl ) amino )methyl; gr33343x; SALMETEROL (SUBJECTTOPATENTFREE); SAMETEROL
CAS	89365-50-4
MF	C25H37NO4
MW	415.57

Salmeterol Chemical Properties

Melting point	75.5-76.5°
Boiling point	603.0±55.0 °C(Predicted)
density	1.112±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	9.99±0.31(Predicted)
form	Solid
color	White to Off-White

Salmeterol Usage And Synthesis

Uses	It is used for the long-term prevention and treatment of asthma, chronic bronchitis, and emphysema with reversible airway obstruction.
Definition	ChEBI: A phenol having a hydroxymethyl group at C-2 and a 1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl group at C-4; derivative of phenylethanolamine.

Salmeterol is a novel, selective, long-acting β 2 receptor agonist, with a single bronchodilation dose lasting for 12 hours. There is also a powerful inhibition of the release of lung hypermast cells, which can inhibit the early and late phase response induced by inhalation antigen, and reduce airway hyperreactivity. For asthma (including nocturnal asthma and exercise asthma), wheeze bronchitis, and reversible airway obstruction.

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Salmeterol CAS NO.89365-50-4

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