2,4,5-Trifluorophenylacetic Acid CAS NO.209995-38-0

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2,4,5-Trifluorophenylacetic Acid CAS NO.209995-38-0
Details
MF:C8H5F3O2
MW:190.12
EINECS:606-684-2
Category
Sitagliptin Intermediates
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Description
2,4,5-Trifluorophenylacetic acid Basic information
Product Name: 2,4,5-Trifluorophenylacetic acid
Synonyms: trifluorophenylacetic acid; 2 - (3,4-difluorophenyl) - 2 - fluoroacetic acid; 2,4,5 - Trifluorophenylacetic acid (Sitagliptin); RARECHEM AL BO 0510; 2,4,5 - TRIFLUOROPHENYLACETIC ACID; 2,4,5 - Trifluorophenylaceticacid 97%; Two, four, five, three fluorine benzene acetic acid
CAS: 209995-38-0
MF: C8H5F3O2
MW: 190.12
EINECS: 606-684-2

 

2,4,5-Trifluorophenylacetic acid Chemical Properties

Melting point  121-125 °C
Boiling point 255.0±35.0 °C(Predicted)
density 1.468±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 3.78±0.10(Predicted)
color White to Off-White

 

2,4,5-Trifluorophenylacetic acid Usage And Synthesis

Chemical Properties White to light brown solid
Uses 2,4,5-Trifluorobenzeneacetic Acid is used in the synthesis of EGFR/ErbB-2-kinase inhibitors. Also used in the synthesis of new imidazopyrazinone derivatives as potnetial dipeptidyl peptidase IV inhibitors.

 

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