Basic Information
|
Product Name |
2-Cyano-5-Fluorobenzyl Bromide |
|
Synonyms |
2-(bromomethyl)-4-fluorobenzonitrile; 2-Cyano-5-fluorobenzyl bromide. |
|
CAS |
421552-12-7 |
|
MF |
C8H5BrFN |
|
MW |
214.03400 |
Physical and chemical properties
|
Melting Point |
No Information |
|
Storage Temp. |
Normal ambient temperature |
|
Appearance |
Null |
|
Density |
1.591g/cm3 |
|
Boiling Point |
264.468ºC at 760 mmHg |
|
Flash Point |
113.746ºC |
Usage
|
Uses |
Used as pharmaceutical intermediate |
Due to its special molecular structure, troglitin is metabolized very slowly in the body, mainly by the kidney. After the drug is metabolized in the body for a week, it can still effectively inhibit the DPP-4 enzyme. Some studies have found that the effect of troglitazone on inhibiting DPP-4 enzyme can still reach about 70% after one week, and it is still the effective solubility of the drug. This is the basis of its once-a-week administration.
Our domestic DPP-4 inhibition is a daily preparation, which needs to be taken daily, once or twice a day.
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