Adenosine CAS No. 58-61-7

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Adenosine CAS No. 58-61-7
Details
MF: C10H13N5O4
MW: 267.24
EINECS: 200-389-9
Category
Tenofovir Intermediates
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Description

Adenosine Basic information

Product Name:

Adenosine

Synonyms:

D-ADENOSINE;AR;(2R,3R,4S,5R)-2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL;9-BETA-D-RIBOFURANOSYLADENINE;Adenine riboside, Adenine-9-beta-ribofuranoside;ADENOSINE extrapure for biochemistry;9-β-D-Ribofuranosyladenine, Adenine riboside, Adenine-9-β-D-ribofuranoside;ADENINENUCLEOSIDE

CAS:

58-61-7

MF:

C10H13N5O4

MW:

267.24

EINECS:

200-389-9

 

Adenosine Chemical Properties

Melting point

234-236 °C(lit.)

Boiling point

410.43°C (rough estimate)

alpha

D11 -61.7° (c = 0.706 in water); 9D -58.2° (c = 0.658 in water)

density

1.3382 (rough estimate)

refractive index

1.7610 (estimate)

storage temp.

2-8°C

solubility

Slightly soluble in water, soluble in hot water, practically insoluble in ethanol (96 per cent) and in methylene chloride. It dissolves in dilute mineral acids.

form

Crystalline Powder

pka

3.6, 12.4(at 25℃)

color

White

optical activity

[α]20/D 70±3°, c = 2% in 5% NaOH

Water Solubility

Soluble in water, ammonium hydroxide and dimethyl sulfoxide. Insoluble in ethanol.

Merck

14,153

BRN

93029

Stability:

Stable. Incompatible with strong oxidizing agents.

 

Adenosine Usage And Synthesis

Defination

Adenosine is a natural nucleotide, which is the intermediate product of metabolism, chemically 6-amino-9-beta-D-ribofuranosyl-9-H-purine. Adenosine is one of the important active components in the body, helps in cellular energy transfer by forming molecules like adenosine triphosphate (ATP) and adenosine diphosphate (ADP). It also plays a role in signaling various pathways and functions in the body by forming signally molecules like cyclic adenosine monophosphate (cAMP).

Chemical Properties

Adenosine is an important nucleoside composed of adenine and ribose. White, crystalline, odorless powder, mild, saline, or bitter taste, quite soluble in hot water, practically insoluble in alcohol. Formed by isolation following hydrolysis of yeast nucleic acid.

White or almost white, crystalline powder.

Uses

adenosine is an amino acid. Studies indicate anti-wrinkle and skinsmoothing capacities. Although little is written about its direct skin benefit, adenosine plays an important role in biochemical processes. As adenosine triphosphate (ATP) and adenosine diphosphate (ADP), it is involved in energy transfer, and as cyclic adenosine monophosphate (cAMP) in signal transduction.

Uses

Nucleotide.antiarrhythmic, cardiac depressant

Medicine Analysis

Method name: Ganoderma Lucidum Oral Liquid-Determination of adenosine-High performance liquid chromatography

Scope of application: This method uses high performance liquid chromatography to determine the content of adenosine in ganoderma lucidum oral solution.

This method is suitable for Ganoderma Lucidum Oral Liquid.

Principle of the method: The test product is added with methanol, ultrasonically treated, and left to be completely precipitated, filtered, and the filtrate is evaporated to dryness, the residue is dissolved with water, extracted with water-saturated n-butanol, the n-butanol extract is evaporated, and the residue Dissolve 50% methanol and dilute to volume. Shake well as a test solution. Inject into a high-performance liquid chromatograph, detect with an ultraviolet detector, the detection wavelength is 260nm, record the response value of adenosine, and calculate its content.

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