Cefuroxime sodium Basic information
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Product Name: |
Cefuroxime sodium |
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Synonyms: |
sodium [6r-[6a,7b(z)]]-3-[[(aminocarbonyl)oxy]methyl]-7-[2-furyl(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;CEFUROXIME NA;CEFUROXIME SODIUM;CEFUROXIME SODIUM SALT;Zinace;5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 3-(aminocarbonyl)oxymethyl-7-(2Z)-2-furanyl(methoxyimino)acetylamino-8-oxo-, monosodium salt, (6R,7R)-;(6R)-3-[(Carbamoyloxy)methyl]-7α-[[2-furanyl[(Z)-methoxyimino]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt;7β-[[(Z)-2-(2-Furyl)-2-(methoxyimino)-1-oxoethyl]amino]-3-[(carbamoyloxy)methyl]cepham-3-ene-4-carboxylic acid sodium salt |
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CAS: |
56238-63-2 |
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MF: |
C16H15N4O8S.Na |
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MW: |
446.37 |
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EINECS: |
260-073-1 |
Cefuroxime sodium Chemical Properties
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Melting point |
240-245°C(dec) |
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alpha |
D20 +60° (c = 0.91 in water) |
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storage temp. |
Inert atmosphere,2-8°C |
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solubility |
Freely soluble in water, very slightly soluble in ethanol (96 per cent). |
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form |
neat |
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pka |
pKa (water): 2.5; (DMF): 5.1(at 25℃) |
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Water Solubility |
White to Pale Beige |
Cefuroxime sodium Usage And Synthesis
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Chemical Properties |
White Crystalline Solid |
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Uses |
Cephalosporin antibacterial. Cefuroxime Sodium Salt is an antibacterial. |
Cefuroxime sodium Specification
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Appearance |
White to faintly yellow?powder |
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Identification |
A: The chromatogram of the Assay preparation obtained as directed in the Assay exhibits a major peak for Cefuroxime, the retention time of which corresponds |
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pH |
6.0-8.5 |
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water |
≤3.5% |
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Residual Solvents |
|
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Methanol |
≤3000ppm |
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Acetone |
≤5000ppm |
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Bacterial endotoxins |
≤0.10 EU/mg |
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Assay % |
855µg/mg to 1000µg/mg of Cefuroxime(C16H16N4O8S), calculated on the anhydrous basis. |
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Sterility |
It meets the requirements when tested as directed for Membrane Filtration under test Sterility of the product to be Examined. |
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