Dicyclohexylcarbodiimide Basic information
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Product Name:
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Dicyclohexylcarbodiimide
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Synonyms:
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N,N'-Dicyclohexylcarbodiimide[forPeptideSynthesis];
N,N'-Dicyclohexylcarbodiimide,0.1Msol.inDCM,peptidesynthesisgrade;
N,N'-Dicyclohexylcarbodiimide,1Msolutionindichloromethane;
N,N'-DiChemicalbookcyclohexylcarbodiimide,1Msol.InN-methylpyrrolidone,peptidesynth.grade;
N,N'-Dicyclohexylcarbodiimide,>98%;dccsolution;
n,n'-dicyclohexylcarbodiimidesolution;DCCDicyclohexylcarbodiimide
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CAS:
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538-75-0
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MF:
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C13H22N2
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MW:
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206.33
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EINECS:
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208-704-1
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Dicyclohexylcarbodiimide Chemical Properties
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Melting point
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34-35 °C(lit.)
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Boiling point
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122-124 °C6 mm Hg(lit.)
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density
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1.247 g/mL at 25 °C
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refractive index
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n20/D 1.48
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Fp
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190 °F
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storage temp.
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Store below +30℃
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solubility
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methylene chloride: 0.1 g/mL, clear, colorless
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form
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Waxy Solid or Crystalline Mass
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color
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White to pale yellow
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Specific Gravity
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1.247
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Water Solubility
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Reaction
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Sensitive
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Moisture Sensitive
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Merck
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14,3096
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BRN
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610662
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Stability:
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Stable, but moisture sensitive. Combustible. Incompatible with strong oxidizing agents. Avoid exposure to air or moisture.
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Dicyclohexylcarbodiimide Usage And Synthesis
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Description
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Dicydohexyl carbodiimide is used in peptide chemistry as a coupling reagent. It is both an irritant and a sensitizer, and caused contact dermatitis in pharmacists and chemists.
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Chemical Properties
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N,N0 -Dicyclohexylcarbodiimide (DCC) is a white crystalline solid. Odor is sweet and heavy.
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Uses
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In the synthesis of peptides.
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Uses
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This product is mainly used in amikacin, glutathione dehydrants, as well as in synthesis of acid anhydride, aldehyde, ketone, isocyanate; when it is used as dehydrating condensing agent, it reacts to dicyclohexylurea through short-time reaction under normal temperature. This product can also be used in synthesis of peptide and nucleic acid. It is easy to use this product to react with compound of free carboxy and amino-group into peptide. This product is widely used in medical, health, make-up and biological products, and other synthetic fields.
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Uses
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N,N'-Dicyclohexylcarbodiimide is a carbodiimide used to couple amino acids during peptide synthesis. N,N'-Dicyclohexylcarbodiimide is used as a dehydrating agent for the preparation of amides, ketones , nitriles as well as in the inversion and esterification of secondary alcohols.
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Uses
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dicyclohexylcarbodiimide is used as a dehydrating agent at room temperature after a short reaction time, after the reaction product is dicyclohexylurea. the product is very small solubility in an organic solvent, so that easy separation of the reaction product.
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Shipping
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UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1- Poisonous materials, Technical Name Required
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Dicyclohexylcarbodiimide Specification
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Appearance
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White to primrose crystal or
transparent liquid |
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Content
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≥99.0%
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Melting point
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32-36℃
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Residue on ignition
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≤0.10%
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Insoluble matter in acetone
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None
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