Basic information
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Product Name: |
(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane |
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Synonyms: |
tert-Butyl[(S)-1-[(S)-Oxiran-2-yl]-2-phenylethyl]carbamate(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane;(2R,3S)-1,2-Epoxy-3-(Boc-aMino)-4-phenylbutane,95+%;(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane99%;(2S,3S)-3-Boc-amino-1,2-epoxy-4-phChemicalbookenylbutane,>=99%;3S-(T-BOC)AMINO-1,2-(S)-EPOXY-4-PHENYLBUTANE;[(1S)-1-((2S)-Oxiranyl)-2-phenylethyl]carbaMicAcidtert-Butyl;TERT-BUTYL[S-(R,R)]-(-)-(1-OXIRANYL-2-PHENYLETHYL)CARBAMATE;T-BUTYL[S-(R*,R*)]-(-)-(1-OXIRANYL-2-PHENYLETHYL)CARBAMATE |
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CAS: |
98737-29-2 |
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MF: |
C15H21NO3 |
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MW: |
263.33 |
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EINECS: |
425-420-5 |
Physical and chemical properties
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Melting point |
125-127 °C(lit.) |
|
alpha |
-7°(23℃, c=0.6, CH3OH) |
| Boiling point | 398.8±25.0 °C(Predicted) |
| density | 1.118±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer,under -20℃ |
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form |
powder to crystal |
| pka | 12.19±0.46(Predicted) |
| color | White to Almost white |
| optical activity | [α]23/D 7°, c = 0.6 in methanol |
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Water Solubility |
Insoluble in water. Soluble in Chloroform, Dichloromethane and Ethyl Acetate. |
Usage
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Uses |
It function as a building block employed in the synthesis of HIV-1 protease inhibitors and is also employed in synthesizing (hydroxyethyl)urea peptidomimetrics and arylsulfonamides possessing anti-HIV activity. It is a Enantiomer S. Atazanavir intermediate. |
1-benzyl-2,3-epoxy n-propyl-tert-butyl carbamate can be used in pharmaceutical intermediates, pharmaceutical extractants, and many raw ingredients used in the production of medical drugs contain 1-benzyl-2-3-epoxy n-propyl-tert-butyl carbamate, such as the synthesis of amprenavir drugs and alcohol magnesium compounds.1-Benzyl-2,3-epoxy orthopropyl-tertiary butyl ester in epoxy polyamide coatings can replace a large amount of xylene, neither affecting the performance of the coating, and can greatly reduce the harmful substances in the coating release and produce the amount of ozone.1-benzyl-2,3-epoxy orthopropyl-tert-butyl carbamate can reduce the viscosity of coatings, such as those used in polyurethane coatings and alkyd coatings. Its coatings are generally widely used in decoration and industry. In addition, 1-benzyl-2,3-epoxy n-propyl-tertiary-butyl carbamate is generally a solvent type of industrial cleaning agent, and chloride solvent, hydrocarbon solvents have similar dissolution effect, but will not destroy the ozone layer, can be used in industrial related equipment cleaning and some metal defat, so it is mainly solvent type cleaning.
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