Adenine Basic information
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Product Name: |
Adenine |
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Synonyms: |
Adenin;Adeninimine;Leuco-4;Purine, 6-amino-;USAF CB-18;usafcb-18;vitaminb4(adenine);ADENINE FREE BASE PLANT TISSUE CULTURETE STED |
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CAS: |
73-24-5 |
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MF: |
C5H5N5 |
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MW: |
135.13 |
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EINECS: |
200-796-1 |
Adenine Chemical Properties
| Melting point | >360 °C (lit.) |
| Boiling point | 238.81°C (rough estimate) |
| density | 1.3795 (rough estimate) |
| refractive index | 1.7000 (estimate) |
| Fp | 220°C |
| storage temp. | 2-8°C |
| solubility | 0.5 M HCl: soluble20mg/mL, Grade III, colorless to faint yellow or tan |
| pka | 4.12(at 25℃) |
| form | Liquid or Solid |
| color | Clear colorless to light yellow |
| Odor | Odorless |
| PH Range | 7 |
| Water Solubility | 0.5 g/L (20 ºC) |
| Sublimation | 220℃ |
| Merck | 14,152 |
| BRN | 5777 |
| Stability | Stable. Moisture-sensitive. Incompatible with strong oxidizing agents. |
| InChIKey | GFFGJBXGBJISGV-UHFFFAOYSA-N |
| LogP | -0.090 |
Adenine Usage And Synthesis
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Description |
adenine is one of the purine nitrogenous bases that composes DNA and RNA; composed of two carbon–nitrogen rings. Adenine bonds with thymine in DNA and with uracil in RNA (see base pairing rule); it is also a major component of other molecules such as adenosine triphosphate. | |
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Chemical Properties |
Adenine is a prominent member of the family of naturally occurring purines. Adenine occurs not only in ribonucleic acids (RNA), and deoxyribonucleic acids (DNA), but in nucleosides, such as adenosine, and nucleotides, such as adenylic acid, which may be linked with enzymatic functions quite apart from nucleic acids. Adenine, in the form of its ribonucleotide, is produced in mammals and fowls endogenously from smaller molecules and no nutritional essentiality is ascribed to it. In the nucleosides, nucleotides, and nucleic acids, the attachment or the sugar moiety is at position 9. The purines and pyrimidines absorb ultraviolet light readily, with absorption peaks at characteristic frequencies. This has aided in their identification and quantitative determination. |
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Uses |
Adenine is used as an active component of boron-deficient media to grow yeast in order to assess whether yeast growth is stimulated by boron. It is useful as a local antiseptic and vitamin B4. Further, it is used in the microbial determination of niacin. It is also employed as a food supplement for adult rats to investigate the effects of dietary adenine overload. In addition to this, it is used in the production of nucleotides of the nucleic acids. | |
Adenine Specification
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Description |
white or white crystalline powder |
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Loss on drying |
≤1.0% |
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Crude Ash |
≤0.1% |
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Heavy Metal |
≤10ppm |
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Single realted |
≤0.5% |
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Purity |
≥99.0% |
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Assay |
98.0-102.0% |
Widespread throughout animal and plant tissues combined with niacinamide, d-ribose, and phosphoric acids; a constituent of nucleic acids and coenzymes, such as codehydrase I and II, adenylic acid, coa laninedehydrase. It is used in microbial determination of niacin; in research on heredity, virus diseases, and cancer.
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