Uracil Basic information
|
Product Name: |
Uracil |
|
Synonyms: |
COATED SAFETY BOTTLE 2,5LWITHOUT CAP ISO;ALUMINIUM CAN WITH HANDLE AND STOPPER;Uracyl;2,6-Dihydroxypyrimidine;2-Hydroxy-4(3H)-pyrimidinone;4-Hydroxy-2(1H)-pyrimidinone;Hybar X;hybarx |
|
CAS: |
66-22-8 |
|
MF: |
C4H4N2O2 |
|
MW: |
112.09 |
|
EINECS: |
200-621-9 |
Uracil Chemical Properties
|
Melting point |
>300 °C(lit.) |
|
Boiling point |
209.98°C (rough estimate) |
|
density |
1.4421 (rough estimate) |
|
refractive index |
1.4610 (estimate) |
|
storage temp. |
2-8°C |
|
form |
Crystalline Powder |
|
pka |
9.45(at 25℃) |
|
color |
White to slightly yellow |
|
Water Solubility |
SOLUBLE IN HOT WATER |
|
Merck |
14,9850 |
|
BRN |
606623 |
|
Stability: |
Stable. Incompatible with strong oxidizing agents. |
Uracil Usage And Synthesis
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Chemical Properties |
Crystalline needles. Soluble in hot water, ammonium hydroxide, and other alkalies; insoluble in alcohol and ether. |
|
Uses |
Antineoplastic Nitrogenous base on RNA nucleosides. |
Uracil is a unique base of RNA and is equivalent to thymine (T) in DNA. In the process of DNA transcription, the DNA is unwound by helicase in the nucleus, and then paired with free base pairs to form a single-stranded RNA, which becomes messenger RNA (mRNA). In this process, the base pairing principle is: A-U, C-G, T-A, G-C. One of the pyrimidine bases, together with cytosine, is a component of RNA. It is also contained in important precursors of polysaccharides such as uridine diphosphate glucose. Shows specific UV absorption (maximum 259 nm). The main difference between RNA and DNA is the difference in sugar composition. RNA contains uracil and DNA contains thymine.
Prepared by the reaction of malic acid, sulfuric acid and urea
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