Gefitinib Information
| Product Name: | Gefitinib |
| Synonyms: | N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amineGefitinib; N-(3-Chlor-4-fluorophenyl)-7-[methoxy-6-[(3-morpholin-4-yl)propoxyl]-quinazolin-4-yl]amine; GEFITINIB RELATED COMPOUND; Gefitinib N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine; IRESSA; n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine |
| CAS: | 184475-35-2 |
| MF: | C22H24ClFN4O3 |
| MW: | 446.9 |
| EINECS: | 643-034-7 |
Gefitinib Chemical Properties
| Melting point | 119-120 °C |
| Boiling point | 586.8±50.0 °C(Predicted) |
| Density | 1.322±0.06 g/cm3(Predicted) |
| Storage temp. | Room temp |
| Solubility | Soluble in DMSO (up to 40 mg/ml) or ethanol (up to 4 mg/ml). |
| Pka | 7.00±0.10(Predicted) |
|
Form |
Powder |
|
Color |
White to beige |
Gefitinib Usage
| Uses | Gefitinib is a highly specific anti-tumor targeted therapeutic drug developed by AstraZeneca in the UK. It is the first molecular targeted drug used for the treatment of non-small cell lung cancer (Chemicalbook). It exerts its effect by selectively inhibiting the signaling pathway of the epidermal growth factor receptor tyrosine kinase (EGFR-TK). |
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