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Name
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Ceftobiprole medocaril
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|---|---|
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Synonyms
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Ceftobiprole medocaril; 5 - Thia - 1 - azabicyclo[4.2.0]oct - 2 - ene - 2 - carboxylic acid, 7 - [((2Z) - 2 - (5 - amino - 1,2,4 - thiadiazol - 3 - yl)-2 - (hydroxyimino)acetyl]amino]-3 - [([3 - ethyl - 1'(5 - methyl - 2 - oxo - 1,3 - dioxol - 4 - ylmethyl)oxy]carbonyl]-2 - oxo[1,3' - bipyridinidin]-3 - ylidene)methyl]-8 - oxo-, (6R,7R) - BAL5788; Ceftobiprole medocaril USP/EP/BP; 5 - Thia - 1 - azabicyclo[4.2.0]oct - 2 - ene - 2 - carboxylic acid, 7 - [((2Z) - 2 - (5 - amino - 1,2,4 - thiadiazol - 3 - yl)-2 - (hydroxyimino)acetyl]amino]-3 - [([3 - ethyl - 1'(5 - methyl - 2 - oxo - 1,3 - dioxol - 4 - ylmethyl)oxy]carbonyl]-2 - oxo[1; BAL - 5788, Inhibitor, penicillin, cephalosporin, inhibit, gram - positive, pyrrolidinone, BAL 5788, MRSA, Ceftobiprole medocaril, Bacterial, vancomycin, pathogens, staphylococci, gram - negative, VRSA, methicillin, Prodrug; Valine Impurity 146
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CAS
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376653 - 43 - 9
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MF
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C₂₆H₂₆N₈O₁₁S₂
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MW
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690.66
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Density
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1.95
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pKa (Acidity Coefficient)
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2.46 ± 0.50 (Predicted)
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Usage
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1.Treating complicated skin and skin structure infections, an indication approved for marketing in Canada and Switzerland.
2.Addressing infections caused by drug-resistant bacteria such as Methicillin-Resistant Staphylococcus Aureus (MRSA) and Vancomycin-Resistant Staphylococcus Aureus (VRSA) – it is currently the only cephalosporin antibiotic effective against these resistant strains.
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