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Product Name:
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Pyrimidinetetramine sulfate |
| Synonyms: |
pyrimidinetetrayltetraaminesulphate;
PYRIMIDINE-2,4,5,6-TETRAMINESULPHATE; 2,4,5,6-TETRAAMINIOPYRIMIDINESULFATE; 2,4,5,6-TETRAAMINO-PYRIMIDINESULFATESALT;
2,4,5,6-Tetraaminopyrimidinesulfatehydrate,98%; 2,4,5,6-Tetraaminopyrimidinesulfate;
6-TetraaMinopyriMidinesulfate;
PyriMidine-2,4,5,6-tetraaMinesulfate
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CAS:
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5392-28-9 |
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MF:
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C4H10N6O4S |
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MW:
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238.22 |
| EINECS： | 226-393-0 |
Pyrimidinetetramine sulfate
| Melting Point | >300 °C(lit.) |
| Water Solubility | slightly soluble |
| Solubility | DMSO (slight, with heating), water (very slight, with heating) |
| Form | Crystalline powder |
| Color | Ochre to brown |
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Storage temp.
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Sealed in dry,Room Temperature |
Usage
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Uses
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2,4,5,6-Tetraaminopyrimidine sulfate is an intermediate for the synthesis of the antineoplastic drugs methotrexate and fludarabine.Methotrexate is a folate-based antineoplastic agent, mainly used for tumors such as acute leukemia, breast cancer, choriocarcinoma, and liver cancer, as well as autoimmune-related diseases including post-transplant rejection, dermatomyositis, and systemic lupus erythematosus.Fludarabine exhibits significant efficacy in the treatment of B-cell chronic lymphocytic leukemia.
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