Trifluoroacetic acid Basic information
|
Product Name: |
Trifluoroacetic acid |
|
Synonyms: |
R3, TRIFLUOROACETIC ACID;R4A, TRIFLUOROACETIC ACID;RARECHEM AL BO 0421;PERFLUOROACETIC ACID;TFA;TRIFLUOROACETIC ACID;TRIFLUOROACETLC ACID;WASH BUFFER |
|
CAS: |
76-05-1 |
|
MF: |
C2HF3O2 |
|
MW: |
114.02 |
|
EINECS: |
200-929-3 |
Trifluoroacetic acid Chemical Properties
|
Melting point |
-15.4 °C(lit.) |
|
Boiling point |
72.4 °C(lit.) |
|
density |
1.489 g/mL at 20 °C(lit.) |
|
vapor density |
3.9 (vs air) |
|
vapor pressure |
97.5 mm Hg ( 20 °C) |
|
refractive index |
n20/D 1.3(lit.) |
|
Fp |
None |
|
storage temp. |
Store at +15°C to +25°C. |
|
solubility |
Miscible with ether, acetone, ethanol, benzene, hexane, and CCl4 |
|
pka |
-0.3(at 25℃) |
|
form |
Liquid |
|
Specific Gravity |
1.480 |
|
color |
Colorless |
|
PH |
1 (10g/l, H2O) |
| PH Range | 1 |
|
Odor |
Sharp, pungent odor |
|
Water Solubility |
miscible |
|
Sensitive |
Hygroscopic |
|
Stability: |
Stable. Incompatible with combustible material, strong bases, water, strong oxidizing agents. Non-combustible. Hygroscopic. May react violently with bases. |
Trifluoroacetic acid Usage And Synthesis
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Uses |
Mainly used as an fluorine-containing intermediate in fine chemical, pharmaceutical, pesticide and dye. It is used as a raw material in the process of glass coating , sugar and polypeptide synthetic. It is used as a catalyst in esterification reaction and condensation reaction and a protective agent for hydroxyl and amino. |
|
Uses |
Suitable for peptide and protein synthesis. |
|
Uses |
In organic synthesis; dissolves protein when mixed with liquid SO2. |
|
General Description |
A colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and as a solvent. |
|
Air & Water Reactions |
Fumes in air. Soluble in water. |
|
storage |
trifluoroacetic acid should be stored in an acid cabinet away from other classes of compounds. Because of its high vapor pressure, fumes of trifluoroacetic acid can destroy labels on other bottles if the container is not tightly sealed. |
Trifluoroacetic acid Specification
|
Product appearance |
Clear colorless liquid |
|
CF3COOH |
≥99.5% |
|
HCl |
≤0.05% |
|
H2SO4 |
≤0.05% |
|
HF |
≤0.002% |
|
H2SO3 |
≤0.05% |
|
Water |
≤0.05% |
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