Basic information
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Product Name: |
Fusidine |
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Synonyms: |
4-alpha,8-alpha,9-beta,11-alpha,13-alpha,14-beta,16-beta,17z)-ph;ramycin;sq16603;(3ALPHA,4ALPHA,8ALPHA,9BETA,11ALPHA,13ALPHA,14BETA,16BETA,17Z)-16-(ACETYLOXY)-3,11-DIHYDROXY-29-NORDAMMARA-17(Chemicalbook20),24-DIEN-21-OICACID;FUSIDICACID;Fusidicacidforpeakidentification;Fusidicacid,98.5% |
|
CAS: |
6990-06-3 |
|
MF: |
C31H48O6 |
|
MW: |
516.71 |
Physical and Chemical Properties
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Melting point |
190-192°C |
| Boiling point | 635ºC |
| Density | 1.16g/cm3 |
|
Appearance |
White solid |
Indications
| Clostridium sporionic acid class of antibiotics | Fusidic acid, also known as fusoxysporic acid, sodium fusoxysporate, sodium fusoxysporate, fusomycin or steroidomycin, is a kind of fusoxysporic acid antibiotic with steroidal skeleton, its chemical structure is similar to cephalosporin P, is not a hormone, produced by fusoxyspora globosa in fungi or some cephalosporus. The antibacterial spectrum was narrow, similar to that of neomycin, but the effect on Bacteroidesfragilis was obvious, while the effect on Streptococcus and Streptococcus pneumoniae was weak. Its mechanism of action is to inhibit bacterial protein synthesis, play bacteriostatic or bactericidal effect. It has strong antibacterial effect on Staphylococcus (including methicillin resistant strains or other antibiotic resistant strains), Streptococcus, Enterococcus, diphtheria bacillus, Clostridium difficile, Neisseria genus and Mycobacterium tuberculosis, and has a certain antibacterial effect on Bacteroides fragility. All GRAM-negative bacteria were resistant to the drug except NeisSERia GONorrhoeae, NeISSERia meningitiDIS, Clostridium DIFFICile, AND Bacteroid FLIMSIDIae which were sensitive to THE drug. In vitro, staphylococci are susceptible to drug resistance. There is no cross-resistance between the bacteria and other anti-infective drugs. |
| Indications | For drug-resistant staphylococcus aureus infection, such as pneumonia, osteomyelitis, septicemia, etc. Severe patients need intravenous administration and should be combined with other anti staphylococcal drugs. For the treatment of infected wounds. |
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use |
Sodium salt is usually made for clinical application, and the molecular formula of sodium salt is C31H47NaO6. Fusidic acid is highly sensitive to various Gram-positive cocci associated with skin infections, especially Chemicalbook Staphylococcus. Fusidic acid is also effective against drug-resistant Staphylococcus aureus, and has some antibacterial effects against some Gram-negative bacteria. There is no cross resistance with other antibiotics |
Fusidine CAS NO.6990-06-3 is an antibiotic with steroidal skeleton, which inhibits bacterial protein synthesis. It can inhibit or kill bacteria. It has strong antibacterial effect on Staphylococcus (including methicillin-resistant strains or other antibiotic resistant strains), Streptococcus, Enterococcus, diphtheria, Clostridium, Neisseria and Mycobacterium tuberculosis, but weak against Bacteroides fragilis.
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