Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate CAS NO.:139481-44-0

630.4 ± 65.0 °C at 760 mmHg

1-[(2'-Cyano biphenyl-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid methyl ester is a pharmaceutical active ingredient primarily used in the medical field. This compound serves as a key intermediate or active component in many angiotensin II receptor antagonist (ARB) class drugs, such as valsartan and other antihypertensive medications. These drugs work by selectively blocking the binding of angiotensin II to its receptors, thereby dilating blood vessels and lowering blood pressure. Clinically, they are widely used to treat hypertension, heart failure, and prevent cardiovascular diseases. Therefore, this compound holds significant value in the pharmaceutical industry and is an important synthetic precursor or core structural unit for preparing various antihypertensive and cardiovascular therapeutic drugs.