![CAS：2212021-83-3 5-[(S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl]-1-[(1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl]-1H-indole-2-carboxylic Acid](/uploads/24095/cas-2212021-83-3bc847.png)
![CAS：2212021-83-3 5-[(S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl]-1-[(1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl]-1H-indole-2-carboxylic Acid suppliers](/uploads/24095/cas-2212021-83-3d0932.png "CAS：2212021-83-3 5-[(S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl]-1-[(1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl]-1H-indole-2-carboxylic Acid suppliers")
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Name
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5 - [(S)-(S)-2,2 - Dimethyltetrahydro - 2H - pyran - 4 - yl] - 1 - [(1S,2S)-2 - methyl - 1-(5 - oxo - 4,5 - dihydro - 1,2,4 - oxadiazol - 3 - yl)cyclopropyl]-1H - indole - 2 - carboxylic Acid
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Synonyms
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1H - Indole - 2 - carboxylic acid, 1 - [(1S,2S)-1-(2,5 - dihydro - 5 - oxo - 1,2,4 - oxadiazol - 3 - yl)-2 - methyltetrahydro - 2H - pyran-4 - yl]-5 - [(4S)-tetrahydro - 2,2 - dimethyl - 2H - pyran - 4 - yl]-1 - [(1S,2S)-2 - methyl - 1-(5 - oxo - 4,5 - dihydro - 1,2,4 - oxadiazol - 3 - yl)cyclopropyl]-1H - indole - 2 - carboxylic Acid;
1-[(1S,2S)-1-cyano-2-methoxycyclopropyl]-5 - [(4S)-2,2-dimethyltetrahydro - 2H - pyran-4-yl]-N-methyl-N-phenyl-1H-indole-2-carboxamide;1-[(1S,2S)-1-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-2-methylcyclopropyl]-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-1H-indole-2-carboxylic acid;
5 - [(S)-2,2 - Dimethyl - 5 - (4S)-2,2 - dimethyltetrahydro - 2H -pyran -4-yl]-N-methyl-N-phenyl-1H-indole-2-carboxylic acid;5 - [(S)-2,2 - dimethyltetrahydro -2H- pyran -4 -yl]-1-[(1S,2S)-2 -methyl - 1-(5-oxo -4,5-dihydro- 1,2,4 - oxadiazol - 3 - yl)cyclopropyl]-1H - indole - 2 - formic acid;Orforglipron intermediates 5
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CAS No.
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2212021 - 83 - 3
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MF
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C₂₂H₂₅N₃O₅
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MW
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411.46
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Density
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1.48±0.1 g/cm³ (Predicted)
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Form
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Solid
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Acid dissociation constant (pKa)
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4.55±0.30 (Predicted)
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Color
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White to off-white
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Usage
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Key Intermediate for Drug Synthesis: A heterocyclic compound with multiple chiral centers, used to build core scaffolds of antibacterial and anti-inflammatory drugs.
Raw Material for Heterocyclic Drug Optimization: Modifies functional groups to improve drug lipophilicity and metabolic stability, facilitating new drug R&D.
Building Block for Fine Organic Synthesis: Participates in cyclization/substitution reactions to support synthesis of complex bioactive molecules.
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