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Name
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5 - Bromoindole - 2 - carboxylic acid
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|---|---|
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Synonyms
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5 - BROMO - 1H - INDOLE - 2 - CARBOXYLIC ACID;
5 - BROMO - 2 - INDOLECARBOXYLIC ACID;
5 - BROMOINDOLE - 2 - CARBOXYLIC ACID;
1H - INDOLE - 2 - CARBOXYLIC ACID, 5 - BROMO;
indole - 2 - carboxylic acid;
5 - Bromoindole - 2 - carboxylic acid;
5 - BroMo - 1H - indol - 2 - carboxylic acid;
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CAS
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7254 - 19 - 5
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MF
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C9H6BrNO2
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MW
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240.05
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Melting Point
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287 - 288
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Boiling Point
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470.9 ± 25.0 °C (Predicted)
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Density
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1.838 ± 0.06 g/cm³ (Predicted)
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Storage Condition
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-20°C
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Form
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Solid
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Acid Dissociation Constant (pKa)
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4.25 ± 0.30 (Predicted)
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Color
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White to light yellow to light orange
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Usage
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Intermediate for Antitumor Drug R&D: The indole ring is a core scaffold of many antitumor drugs. This compound can be structurally modified via substitution, condensation, and other reactions, used to construct drug molecules targeting tumor cell signaling pathways, facilitating the development of new formulations that inhibit tumor proliferation and induce cancer cell apoptosis.
Raw Material for Anti-inflammatory and Neuroactive Drug Synthesis: Leveraging the biological activity of the indole ring, it serves as a precursor for synthesizing anti-inflammatory and neuromodulatory drugs. Through structural optimization, it can be developed into drugs targeting inflammatory response pathways or neurotransmitter regulation, with potential applications in treating rheumatoid arthritis, neurodegenerative diseases, etc.
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