Ambroxol Hydrochloride CAS NO.23828-92-4

Ambroxol Hydrochloride Basic information

Ambroxol Hydrochloride Chemical Properties

Ambroxol Hydrochloride Usage And Synthesis

Ambroxol hydrochloride (AmbroxolHydrochloride) is the active metabolite of N-demethyl (cyclohexyl, trans-hydroxyl), whose toxicity is lower than that and higher. Ambroxol hydrochloride is by Germany boehringer ingelheim company research and development of mucus solvent, the drug in the first listed in the early 1980s in Germany, then in France, Italy, Japan, Spain and many other countries, is a new generation of mucus solvent, can improve sputum, and has the promotion of lung surfactant and airway secretion and cilia movement. Clinically, it can regulate mucus and mucus secretion, activate cilia swing, easy to dilute sputum, strong Chemicalbook sified mucus outward transportation, easy to discharge. It can also promote the synthesis of lung surfactant to maintain alveolar tension, ensure lung function indicators; promote the penetration of antibiotics to the tissue, increase concentration, enhance sterilization, resist oxidation, reduce the release of inflammatory media, reduce inflammatory reaction, and cooperate with bronchial spasmodic substances to improve the efficacy of spasmodic drugs. Therefore, the drug can be widely used in clinical with respiratory abnormal secretion of acute and chronic respiratory diseases, especially the expectorant treatment of chronic bronchitis, neonatal respiratory distress and pulmonary surgery, with low toxicity, curative effect, and with antibiotics and produce good synergistic effect, as one of the most commonly used expectorant.