Loratadine CAS NO.79794-75-5

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Loratadine CAS NO.79794-75-5
Details
Antihistamines; Histamine H1 receptor antagonists USP/EP/BP/CP DMF GMP
Category
Loratadine API
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Description

Basic information

Product Name:

Loratadine

Synonyms:

CLARATYNE;ethyl4-(8-chloro-5,6-dihydro-11h-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate;4-(8-Chloro-5,6-dihydro-11H-benzo[5, 6]cyclohepta[1,2-b]pyridine-11-ylidene)piperidine-1-carboxylicacidethylester

CAS:

79794-75-5

MF:

C22H23ClN2O2

MW:

382.88

EINECS:

1308068-626-2

Physical and chemical properties

Melting point

134-136°C

Boiling point

531.3ºCat 760 mmHg

Storage Condition

2-8ºC

Appearance

White Powder

Usage

Uses

National Class II anti-allergic new drug, used to relieve nasal and non-nasal symptoms of seasonal allergic rhinitis and relieve chronic urticaria

 

Antihistamine drugs have a high degree of selectivity for peripheral nerve H1 receptors, a strong effect and a long time. Loratadine CAS NO.79794-75-5 is a long-acting tricyclic antihistamine, which competitively inhibits histamine H1 receptor and inhibits allergic symptoms caused by histamine. No obvious anticholinergic and central inhibitory effects. Used to relieve symptoms related to allergic rhinitis, as well as relieve symptoms of chronic urticaria and other allergic skin diseases.

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