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Product Name:
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2'-Deoxycytidine monohydrate |
| Synonyms: |
2(1H)-Pyrimidinone,4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-; 2'-DEOXYCYTIDINEFREEBASE; 2''-Deoxycytidine(and/orunspecifiedsalts); 2-DEOXYCYTIDINEextrapure;2'-Deoxycytidine,98% |
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CAS:
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951-77-9 |
|
MF:
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C9H13N3O4 |
|
MW:
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227.22 |
| EINECS： | 213-454-1 |
| Melting Point | 209-211 °C(lit.) |
| Boiling Point | 368.93°C (rough estimate) |
| Density | 1.3171 (rough estimate) |
| Solubility | H₂O: 50 mg/mL, clear and colorless |
| Form | Crystalline powder |
| Color | White |
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Storage temp.
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Keep the container sealed and store it in a cool, dry place. |
Usage
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Uses
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Antiviral Drug Synthesis: 2'-Deoxycytidine serves as a key precursor for nucleoside analogs, used in antiviral drugs (e.g., derivatives of zidovudine for HIV) to inhibit viral DNA polymerase and block replication. Anticancer Drug Development: As a raw material for antimetabolite anticancer agents (e.g., gemcitabine analogs), it disrupts DNA synthesis to inhibit tumor cell proliferation, with applications in leukemia and lymphoma research. Molecular Biology Research: Used in PCR, sequencing, and other experiments as a modified nucleotide to study DNA mutations or regulate gene expression, such as synthesizing artificial DNA probes. Genetic Disease Therapy Exploration: Acts as a potential component in gene therapy to correct DNA mutations or modulate epigenetic modifications (e.g., DNA methylation), aiding in the treatment of genetic disorders. |
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