|
Name
|
3-Fluorobenzyl chloride
|
|---|---|
|
Synonyms
|
3-Fluorobenzylchloride, 97%; 3-Benzyl;
3-Fluorobenzyl chloride 1-(Chloromethyl)-3-fluorobenzene;
AKOS BBS - 00003858;
ALPHA-CHLORO-M-FLUOROTOLUENE;
ALPHA-CHLORO-3-FLUOROTOLUENE;
A-CHLORO-M-FLUOROTOLUENE;
3-FLUOROBENZYL CHLORIDE
|
|
CAS
|
456-42-8
|
|
MF
|
C₇H₆ClF
|
|
MW
|
144.57
|
|
EINECS
|
207 - 264 - 8
|
|
Melting Point
|
34.5 - 36 °C
|
|
Boiling Point
|
176 - 177 °C
|
|
Density
|
1.194 g/mL at 25 °C (lit.)
|
|
Refractive Index
|
n20/D 1.511 (lit.)
|
|
Flash Point
|
138 °F
|
|
Storage Conditions
|
Store below +30°C.
|
|
Solubility
|
40 g/L
|
|
Form
|
Transparent liquid
|
|
Specific Gravity
|
1.194
|
|
Color
|
Colorless to pale yellow
|
|
Water Solubility
|
40 g/L (20 °C)
|
|
Sensitivity
|
Lachrymatory
|
|
Usage
|
1. Serve as an intermediate to synthesize antibacterial/anti-infective drugs such as quinolones and cephalosporins, enhancing the antibacterial activity and target-binding efficiency of the drugs.
2. Be used to construct the aromatic ring skeleton of targeted antineoplastic drugs (e.g., tyrosine kinase inhibitors), improving the selectivity of the drugs for tumor cells and reducing toxicity.
3. Participate in the synthesis of non-steroidal anti-inflammatory/analgesic drugs (to reduce gastrointestinal irritation) and neurological drugs for treating depression, Parkinson's disease, etc. (to optimize the interaction with neurotransmitter receptors).
|
Hot Tags: 3-fluorobenzyl chloride cas：456-42-8, China, manufacturers, suppliers, factory, custom, wholesale, CAS NO 87 41 2, Fluorocytosine, Tert butyl acetate, Chlorotrimethylsilane, N O Bis trimethylsilyl acetamide, CAS NO 100 52 7
