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Choline glycerophosphate
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Product Name:
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Choline glycerophosphate
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Synonyms:
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2-[[(2R)-2,3-dihydroxypropoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium;
L-A-GLYCEROPHOSPHORYLCHOLINEFROM*EGGYOLKFREEFORM; L-A-GLYCEROPHOSPHORYLCHOLINEFROMSOYBEAChemicalbookN,FREEFORM; L-α-GLYCERYLPHOSPHORYLCHOLINE(GPC);,hydroxide,innersalt,(r)-; L-a-Glycerophosphorylcholine(anhydrous)(GPC);GLYCERYLPHOSPHOCHOLINE;L-A-GLYCEROPHOSPHOCHOLINE |
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CAS:
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28319-77-9
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MF:
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C8H20NO6P
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MW:
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257.22
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EINECS:
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248-962-2
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Choline glycerophosphate
| Melting point | 142.5 - 143 °C |
| Specific rotation | D25 - 2.7° (c = 2.7 in water, pH 2.5); D25 - 2.8° (c = 2.6 in water, pH 5.8) |
| Vapor pressure | 0 Pa at 25 °C |
| Boiling point | 480 °C [at 101 325 Pa] |
| Flash point | 11 °C |
| Solubility | Soluble in DMSO (with gentle, heating, and ultrasonic treatment), methanol (small amount), water (small amount) |
| Water solubility | 1000 g/L at 25 °C |
| Stability | Very hygroscopic |
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Storage temp.
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-20 °C |
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Form
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Solid |
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Color
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White to off-white
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Choline glycerophosphate Usage
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Uses
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Glycerophosphocholine is a naturally occurring intermediate in phospholipid metabolism in the human body. It exists in cells and is distributed throughout the human body. Structurally, it consists of choline, glycerol, and phosphoric acid. It is a major storage form of choline and is recognized as a source of choline. As an endogenous substance, it has extremely low toxicity and side effects. After absorption, glycerophosphocholine is decomposed into choline and glycerophospholipid under the action of enzymes in the body: choline participates in the biosynthesis of acetylcholine (a type of nerve trigger transmitter) as noted in Chemicalbook; glycerophospholipid is a precursor of lecithin and is involved in the synthesis of lecithin. Its main pharmacological effects include protecting the metabolism of choline, ensuring the synthesis of acetylcholine and lecithin in nerve membranes, and improving blood circulation. It can also improve cognitive and behavioral responses in patients with damaged cerebral capillaries. However, in this field, there are no better new drugs on the market or under research and development.
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