CAS:247069-27-8 3,5-Difluoropyridine-2,6-diamine

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CAS:247069-27-8 3,5-Difluoropyridine-2,6-diamine
Details
CAS No. 247069-27-8
MF C5​H5​F2​N3​
MW 145.11
Category
Delafloxacin Intermediates
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Description
 Name
3,5 - Difluoropyridine - 2,6 - diamine
Synonyms
2,6 - DIAMINO - 3,5 - DIFLUOROPYRIDINE;
3,5 - DIFLUOROPYRIDINE - 2,6 - DIAMINE;
2,6 - Pyridinediamine, 3,5 - difluoro - (9CI);
2,6 - diamino - 3,5 - difluoropyridine;
2,6 - Diamino - 3,5 - difluoropyridine;
3,5 - difluoro - 2,6 - Pyridinediamine;
2,6 - Pyridinediamine, 3,5 - difluoro -
CAS No.
247069-27-8
MF
C5​H5​F2​N3​
MW
145.11
EINECS No.
623 - 869 - 3
Melting Point
160°C
Boiling Point
233.3 ± 35.0 °C (Predicted)
Density
1.517 ± 0.06 g/cm³ (Predicted)
Storage Conditions
2 - 8°C, protect from light
Form
solid
Acid dissociation constant (pKa)
1.93 ± 0.10 (Predicted)
Appearance
White to light brown solid
Usage
1. Reagent for Antibacterial Drug Synthesis: It is a key reagent for synthesizing 1-(6-amino-3,5-difluoropyridin-2-yl) fluoroquinolones with anti-mycobacterial and antibacterial activities.
2. Intermediate in Pharmaceutical R&D: As an intermediate in organic synthesis and chemical pharmaceutical R&D, it is mainly used in the synthesis of antitumor drugs (e.g., crizotinib), facilitating the R&D and production of related drugs.

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