Lansoprazole Basic information
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Product Name: |
Lansoprazole |
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Synonyms: |
LANSOPRAZOLE, RELATED COMPOUND A2-[[[3-METHYL-4-(2,2,2-TRIFLOUROETHOXY)-2-PYRIDYL]METHYL]SULFONYL]BENZIMIDAZOLE USP STANDARD;LANSOPRAZOLE, MM(CRM STANDARD);LANSOPRAZOLE USP(CRM STANDARD);2-[3-METHYL-4-(2,2,2-TRIFLUORO-ETHOXY)-PYRIDIN-2-YLMETHANESULFINYL]-1H-BENZOIMIDAZOLE;2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1h-benz;PREVACID;OGAST;LANSOPRAZOLE |
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CAS: |
103577-45-3 |
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MF: |
C16H14F3N3O2S |
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MW: |
369.36 |
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EINECS: |
2017-001-1 |
Lansoprazole Chemical Properties
| Melting point | 178-182°C dec. |
| Boiling point | 555.8±60.0 °C(Predicted) |
| density | 1.50±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, soluble in anhydrous ethanol, very slightly soluble in acetonitrile. |
| pka | pKa 2.34±0.37 (Occasionally);3.53±0.37 (Occasionally);8.48±0.30 (Occasionally) |
| form | powder |
| color | off-white |
| Merck | 14,5362 |
Lansoprazole Usage
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Uses |
For reflux esophagitis, gastric ulcer, and duodenal ulcer. |
Lansoloprazole is a new drug to inhibit gastric acid secretion and basic gastric acid secretion, which has a significant inhibitory effect on gastric acid secretion caused by all stimulants (such as histamine, carbamylcholine, etc.). Its acid inhibitory effect is significantly better than H2 receptor blockers, and the inhibition degree and concentration have a significant dependence on it. Lansoloprazole can quickly turn Chemicalbook into efficacy through the mural cell membrane to subsulfonic acid and subsulfonyl derivatives, inhibiting Helicobacter pylori (Hp), which is four times that of omeprazole. Clinically used in the treatment of duodenal ulcer, gastric ulcer, anastomotic ulcer, reflux esophagitis,Zollinger-Ellison syndrome; gastrinoma), with remarkable curative effect.
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