Creatine Phosphate Disodium Salt Basic information
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Product Name:
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Creatine phosphate disodium salt
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Synonyms:
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Phosphocreatine Sodium Salt Creatine Phosphate Sodium Salt Sodium Phosphocreatine;SodiuM 2-(1-Methylguanidino)acetate hydrogenphosphate tetrahydrate;Glycine,N-[iMino(phosphonoaMino)Methyl]-N-Methyl-, sodiuM salt (1:2);CREATINE PHOSPHATE SODIUM FOR LNJECTION;DISODIUM [(CARBOXYMETHYL)(METHYL)AMINO](IMINO)METHYLAMIDOPHOSPHATE;Sodium Creatine Phosphate Sodium Phosphocreatine Phosphocreatine Sodium Salt;Creatine phosphate disodium salt and Intermediates;SODIUM PHOSPHOCREATINE |
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CAS:
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922-32-7
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MF:
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C4H8N3Na2O5P
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MW:
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235.11
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EINECS:
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213-074-6
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Creatine Phosphate Disodium Salt Chemical Properties
| density | 1.784 at 20℃ |
| vapor pressure | 0.025Pa at 20-50℃ |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | H2O: 0.1 g/mL, clear, colorless |
| form | Powder |
| color | White |
| PH | pH : 8.3 (20% in water) |
| Water Solubility | soluble |
| LogP | -1.17 at 22℃ and pH7 |
Creatine Phosphate Disodium Salt Usage And Synthesis
| Chemical Properties | white powder |
| Description | Creatine phosphate belongs to the human body and is the most important type of energy supplier. It can provide energy support for various tissues and organs. In human brain, kidney, cardiac muscle and skeletal muscle, 80% of the energy source is creatine phosphate. In humans, the synthesis of creatine phosphate begins in the kidney organs. A guanidinic acid is formed from arginine and glycine, and then creatine is formed through methylation in the liver. Finally, it is phosphorylated in various cellular tissues. And creatine phosphate is formed. Creatine phosphate disodium salt is a commercial creatine phosphate drug, which has become more and more widely used in acute myocardial infarction in recent years, and has achieved good results. |
| Uses | Creatine phosphate disodium salt is a white needle-like crystalline powder that is easily soluble in water. In medicine, it can protect the heart muscle by injecting creatine phosphate disodium salt, and can also be used to treat myocardial abnormalities in the ischemic state. creatine phosphate plays an important role in energy metabolism during muscle contraction[3]. The use of creatine phosphate is generally by intravenous injection. Phosphocreatine disodium salt exists as creatine phosphate after entering the body. |
It is an important energy supply substance for muscle contraction and metabolism, and it is also a chemical energy reserve for smooth muscle and striated muscle. It is generally used for the resynthesis of ATP. The chemical name is N-[imino(phosphoamino)methyl]-N-methylglycine disodium salt, which is a cardioprotective agent. The form of creatine phosphate has a variety of important physiological functions and is widely used for myocardial protection in patients with cardiac ischemia or cardiac surgery, as well as for the treatment of cardiovascular diseases such as heart failure, myocardial infarction and arrhythmia. It can improve heart function and heart rate variability in patients with ischemic cardiomyopathy. It can not only provide energy for myocardial cells suffering from ischemia and hypoxia, but also protect myocardial cell membranes from oxygen free radicals and other harmful substances.
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