BMJ Sub Issue: How Much Exercise? To Counteract The Harm Of Sitting For A Long Day

Jun 08, 2023

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Sitting for a long time is one of the most common lifestyles in today's society, and it is also a risk factor for many health conditions. In modern society, being sedentary has become a Social phenomenon. A busy day at work, sitting in front of the computer, going home after a tiring day, watching TV while eating takeout, and waiting for a long time.
The World Health Organization has long listed sedentary behavior as one of the top ten deadly and pathogenic factors, with sedentary behavior being second only to smoking. Early studies have shown that prolonged sitting increases the risk of cancer death, depression, and more.
In November 2020, researchers from the Norwegian College of Sports science and Harvard Medical School published a research paper entitled "Joint associations of accelerated measured physical activity and similar time with all cause mobility: a harmonious meta analysis in more than 44000 middle aged and older individuals" on the British Journal of Sports medicine, a sub journal of BMJ.
This study shows that prolonged sitting increases the risk of death, and 30 to 40 minutes of moderate to high intensity exercise per day can offset the harm caused by 10 hours of sitting. Any amount of exercise can bring some help.
In this study, the researchers conducted a meta-analysis of nine prospective Cohort study from four countries. A total of 44370 male and female participants, with an average age of 65.8 years, were included. The participants' sedentary time and exercise were measured by wearing an accelerometer, and the joint relationship between exercise and sedentary time and all-cause mortality was analyzed.
Among all participants, the average sedentary time ranged from 8.5 to 10.5 hours, and the duration of moderate to high intensity exercise ranged from 8 minutes to 35 minutes.
During an average follow-up period of 6 years, a total of 3451 participants' deaths were recorded.
Overall, the risk of death increases with a decrease in moderate to high intensity exercise levels and an increase in sedentary time.
According to the amount of moderate to high intensity exercise and sedentary time, participants were divided into three groups. The study found that there was no association between sedentary time and a higher risk of death among participants who engaged in moderate to high intensity exercise for 30-40 minutes. As the amount of exercise decreases and sedentary time increases, the risk of death increases.

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The joint association between exercise and sedentary time and all-cause mortality rate
Specifically, compared to the highest intensity group, the risk of death increased by 5%, 31%, and 68% with an increase in sedentary time in the same amount of moderate to high intensity exercise group. Among the population with the lowest amount of exercise, the risk of death increases by 65%, 65%, and 263% with the increase of sedentary time, respectively.
The results showed that there was no significant difference in the risk of death among individuals who exercised from moderate to high intensity for 30 to 40 minutes per day, whether sitting for long or short periods of time, indicating that this can offset the harm caused by sitting for 10 hours.
Moreover, prolonged sitting is associated with a high risk of 12 diseases.
Researchers from Tianjin Medical University published a research paper entitled "Associations of sedentary time and physical activity with opposite health conditions: Outcome wide analyses using isothermal substitution model" on the sub journal "EClinical Medicine" of The Lancet.
The study found that sitting more than 6 hours a day is associated with high risk of 12 diseases, including ischemic heart disease, diabetes, chronic obstructive pulmonary disease, asthma, Chronic kidney disease, chronic liver disease, Thyroid disease, depression, migraine, gout, Rheumatoid arthritis, diverticulum disease.
If participants reduce their daily sedentary time to less than 6 hours, it will prevent approximately 3.7% -22.1% of chronic diseases. If prolonged sitting is replaced by equal amounts of mild, moderate, and vigorous physical activity, the risk of developing 4, 6, and 10 common chronic diseases can be reduced, respectively.
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