Spermidine is a substance present in the body itself. As we age, the level of spermidine in the body decreases. Supplementation of spermidine helps the body continue to clean itself, and old and excess cellular components and harmful invaders such as viruses are broken down and recycled. Finally, it can improve, update and purify cells from the root of cells, so as to avoid various chronic diseases and metabolic diseases caused by cell damage.
autophagy is one of the mechanisms by which cells clear damaged organelles and proteins. It is ubiquitous in eukaryotic organisms and plays an important role in maintaining the metabolic balance of cells.
The word "autophagy" comes from Greek and means "to eat oneself." Simply put, there are denatured or damaged cells in the body that do not contribute to the body, but may also produce toxins that damage normal cells in our body. Autophagy is to reorganize, repair and regenerate the degenerated or damaged cells in the body, so as to achieve cell recycling and reuse, which is of great significance to human health.
Yoshinori Ohsumi, a Japanese scientist who won the Nobel Prize in physiology or medicine, first discovered the mechanism of autophagy in 2016 and identified 15 key genes involved in autophagy.
Studies in top journals such as Science have found that spermidine has a variety of physiological regulatory effects, including autophagy, anti-inflammatory, antioxidant, cardiac protection and neuroprotection, etc., and many physiological processes regulated by spermidine are usually related to the induction of autophagy by spermidine. Spermidine maintains the dynamic balance of cell renewal by activating 15 kinds of autophagy factors in the body.
