Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II) CAS NO.:1375325-71-5

​​Cross - coupling reactions​​: It is a commonly used catalyst for Suzuki - Miyaura coupling, Buchwald - Hartwig coupling, Heck reaction, etc. It can efficiently catalyze the coupling reactions between aryl/vinyl boronic acids and aryl halides, aryl halides and amines, and aryl halides and alkenes, synthesizing biaryls, arylamine compounds, substituted alkenes, etc.

​​Drug synthesis​​: It is used to synthesize intermediates of drugs containing arylamine and biaryl structures, contributing to the preparation of active pharmaceutical ingredients such as anti - tumor drugs, anti - inflammatory drugs, and central nervous system drugs. It can also assist in constructing complex chiral molecules to synthesize chiral drugs.

​​Materials science​​: It plays a role in the synthesis of organic optoelectronic materials and functional polymers. It can be used to catalyze the synthesis of conjugated aromatics and polycyclic aromatics for organic light - emitting diodes and solar cells, as well as high - performance engineering plastics and conductive polymers containing aryl structures.

​​Scientific research​​: As a typical representative of the Pd/P(t- Bu)₃/aminobiphenyl system, it is used for the research on the mechanism of ligand - metal synergy in catalysts. It is also suitable for efficient catalysis under mild conditions in the field of green chemistry.