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Name
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Benzenesulfonamide, 5 - [(2,4 - diamino - 5 - pyrimidinyl)oxy] - 2 - methoxy - 4 - (1 - methylethyl) -, 2 - hydroxy - 1,2,3 - propanetricarboxylate (1:1)
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Synonyms
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Benzenesulfonamide, 5 - [(2,4 - diamino - 5 - pyrimidinyl)oxy] - 2 - methoxy - 4 - (1 - methylethyl) -, 2 - hydroxy - 1,2,3 - propanetricarboxylate (1:1);
Gefapixant citrate; methoxy - 4 - (1 - methylethyl) -, 2 - hydroxy - 1,2,3 - propanetricarboxylate (1:1); Gefapixant Citrat; Jifa Pisheng Citrate
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CAS
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2310299 - 91 - 1
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MF
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C20H27N5O11S
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MW
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545.52
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Form
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Solid
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Color
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White to off-white
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Usage
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Used for treating refractory chronic cough (RCC) in adults, it blocks ATP signaling by antagonizing P2X3 receptors to inhibit cough responses.
Targeting unexplained chronic cough (UCC) in adults, oral administration inhibits sensory nerve activation and relieves related cough symptoms.
As a selective P2X3 receptor antagonist, it regulates respiratory neural signals to meet clinical treatment needs for specific chronic coughs.
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