CAS:865304-71-8 5-(2-isopropyl-4-Methoxy-phenoxy)-pyriMidine-2,4-diaMine

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CAS:865304-71-8 5-(2-isopropyl-4-Methoxy-phenoxy)-pyriMidine-2,4-diaMine
Details
CAS 865304-71-8
MF C14H18N4O2
MW 274.32
Category
Gepirone Intermediate
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Description
 Name
5-(2-isopropyl-4-Methoxy-phenoxy)-pyrimidine-2,4-diamine
Synonyms
TCMDC-132471;EOS-61050;
5-(4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine;
2,4-Pyrimidinediamine, 5-[4-methoxy-2-(1-methylethyl)phenoxy]-;
5-(isopropyl-4-methoxyphenyloxy)pyrimidin-2,4-diamine;
5-(2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine-[AC80386]
CAS 
865304-71-8
MF
C14H18N4O2
MW
274.32
Boiling Point
455.4±55.0 °C
Density
1.218±0.06 g/cm³
pKa(Acidity Coefficient)
7.02±0.10
Usage
As a key intermediate in the synthesis of Gepirone, it constructs the core skeleton of pyrimidine heterocycle and aromatic ring for the target drug, serving as a crucial transitional product in the synthesis process.
With its specific chemical structure, it adapts to nucleophilic substitution, amination and other reactions, facilitating the splicing and modification of key functional groups in the Gepirone molecule.
It supports the central nervous system drug industry chain, providing core raw material guarantee for the industrial production of antidepressant, antitussive and related drugs (such as Gepirone).

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