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Name
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5-(2-isopropyl-4-Methoxy-phenoxy)-pyrimidine-2,4-diamine
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Synonyms
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TCMDC-132471;EOS-61050;
5-(4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine;
2,4-Pyrimidinediamine, 5-[4-methoxy-2-(1-methylethyl)phenoxy]-;
5-(isopropyl-4-methoxyphenyloxy)pyrimidin-2,4-diamine;
5-(2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine-[AC80386]
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CAS
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865304-71-8
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MF
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C14H18N4O2
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MW
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274.32
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Boiling Point
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455.4±55.0 °C
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Density
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1.218±0.06 g/cm³
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pKa(Acidity Coefficient)
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7.02±0.10
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Usage
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As a key intermediate in the synthesis of Gepirone, it constructs the core skeleton of pyrimidine heterocycle and aromatic ring for the target drug, serving as a crucial transitional product in the synthesis process.
With its specific chemical structure, it adapts to nucleophilic substitution, amination and other reactions, facilitating the splicing and modification of key functional groups in the Gepirone molecule.
It supports the central nervous system drug industry chain, providing core raw material guarantee for the industrial production of antidepressant, antitussive and related drugs (such as Gepirone).
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