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Clopidogrel hydrogen sulfate Basic information
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Product Name: |
Clopidogrel hydrogen sulfate |
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Synonyms: |
PLAVIX;SR-25990C,Plavix,Methyl(+)-(S)-a-(2-Chlorophenyl)-6,7-dihydrothieno[3Chemicalbook,2-c]pyridine-5(4H)acetate,Hydrogensulfatesalt;methyl2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetatesulfate;(RS)-Clopidogrelbisulfate |
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CAS: |
135046-48-9 |
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MF: |
C16H16ClNO2S.H2O4S |
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MW: |
419.9 |
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EINECS: |
603-890-4 |
Clopidogrel hydrogen sulfate Physical and Chemical Properties
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Melting point |
184 °C |
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Boiling point |
423.7ºC at 760 mmHg |
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Storage Condition |
2-8℃ |
| Flash Point | 210℃ |
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Form |
Colorless to light yellow liquid |
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Solubility |
DMSO: ~26mg/mL |
Clopidogrel hydrogen sulfate Usage
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Uses |
Used in the synthesis of clopidogrel derivatives as a platelet aggregation inhibitor |
Platelets play a central role in the pathogenesis of acute thrombotic cardiovascular and cerebrovascular events caused by thrombosis caused by atherosclerotic plaque, and this role has been fully studied.
Clopidogrel bisulfate is a new type of anti-platelet aggregation drug similar to ticlopidine. It was successfully developed by the French company Sanofi-Sindrabourg. It is suitable for the prevention and treatment of heart, brain and other diseases caused by high platelet aggregation. Arterial circulatory disorders, such as strokes, myocardial infarctions and peripheral arterial diseases diagnosed in the recent Chemicalbook. It has been widely used in many countries including the United States, Europe and China. This product inhibits platelet activation by inhibiting adenosine diphosphate (ADP) pathway, thereby inhibiting platelet aggregation. Since it takes several days for clopidogrel bisulfate to reach an effective blood concentration, it is not suitable for emergency treatment. After stopping this product for 7 to 10 days, the platelet function can be restored to a normal state.
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