5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one CAS NO.：89-25-8

Edaravone Basic information

Edaravone Physical and Chemical Properties

Edaravone Usage

Edaravone is a new type of free radical scavenger, which was first marketed in Japan in April 2001. It is mainly used clinically to treat ischemic stroke. Edaravone exists in the form of an anion, which can provide 1 Chemicalbook electron to free radicals to achieve the purpose of scavenging free radicals. Because its molecular structure contains lipophilic groups, it is easy to reach the brain tissue through the blood-brain barrier, and has a protective effect on neuronal damage caused by cerebral ischemia.

The protective mechanism of edaravone on nerve cells mainly includes scavenging oxygen free radicals, inhibiting lipid peroxidation, regulating inflammatory factors, and inhibiting cell apoptosis. With the in-depth study of edaravone, it is found that in addition to the treatment of acute cerebral ischemia, edaravone has a therapeutic effect on other diseases of the Chemicalbook nervous system that involve oxidative stress. In addition, edaravone also has a protective effect on other organs besides the nervous system. Edaravone is currently mainly used for the treatment of deficient stroke, but it has less clinical application in other areas.