Ticagrelor CAS NO.274693-27-5

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Ticagrelor CAS NO.274693-27-5
Details
Pyrimidine series; azoles; platelet aggregation inhibitors FDA EU-GMP
Category
Ticagrelor & Ticagrelor Intermediate
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Description

Basic information

Product Name:

Ticagrelor

Synonyms:

 

1,2-Cyclopentanediol,3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-,(1S,2S,3R,5S)-;Brilinta

CAS:

274693-27-5

MF:

C23H28F2N6O4S

MW:

522.57

EINECS:

619-540-9

Physical and Chemical Properties

Melting point

Null

Boiling point

777.551ºC at 760 mmHg

Storage Condition

Keep away from fireworks

Flash Point 424.048℃

Form

Null

Solubility

Null

Usage

Uses

Anticoagulant; used to reduce cardiovascular death and heart attack in patients with acute coronary syndrome (ACS)

 

 

 

Ticagrelor CAS NO.274693-27-5 is a member of the chemical classification cyclopentyltriazopyrimidine (CPTP). CPTP is a selective adenosine diphosphate (ADP) receptor antagonist that acts on the P2Y12ADP receptor to inhibit ADP-mediated platelet activation and Aggregation is similar to the mechanism of action of thienopyridine drugs (such as clopidogrel). But the difference is that the interaction between ticagrelor and the platelet P2Y12 ADP receptor is reversible, there is no conformational change and signal transmission, and the platelet function in the blood is also quickly restored after the drug is stopped.

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