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Name
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α-Lipoic Acid
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|---|---|
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Synonyms
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5 MG PNPP SUBSTRATE TABLETS REAGENT GR; (1)-ALPHA-LIPOIC ACID; DL-α-Lipoic acid USP, 99.0-101.0% (Assay); 5-(1,2)Dithiolan-3-yl-pentanoic acid for synthesis; TIMTEC-BB SBB003484; THIOCTIC ACID; dl-1,2-Dithiolane-3-valeric acid; DL-6-Thioctic acid
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CAS Number
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1077-28-7
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Molecular Formula
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C8H14O2S2
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Molecular Weight
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206.33
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EINECS Number
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214-071-2
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Melting Point
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60-62 °C
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Boiling Point
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160-165 °C (lit.)
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Density
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1.2888 (rough estimate)
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Bulk Density
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260 kg/m³
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Refractive Index
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1.5200 (estimate)
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Flash Point
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160-165°C
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Storage Conditions
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2-8°C
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Solubility
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Ethanol: 50 mg/mL
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pKa
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4.75±0.10 (Predicted)
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Form
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Crystalline or crystalline powder
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Color
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Viscous yellow
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Biological Source
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synthetic
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Water Solubility
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0.9 g/L (20 °C)
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|
Merck
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14,9326
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BRN
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81853
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Stability
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Stable. Incompatible with strong oxidizing agents.
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Usage
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1. Vitamin drugs can stimulate fat metabolism.
2. It is used in the treatment and health maintenance of acute and chronic hepatitis, liver cirrhosis, hepatic coma, fatty liver, diabetes and other diseases. As an antioxidant and a coenzyme for enzymes such as pyruvate dehydrogenase and glycine decarboxylase, exogenous lipoic acid is reduced by two or more enzymes in cells. This reduced form affects the process of cellular free radical scavenging, increases the synthesis of glutathione, regulates the activity of transcription factors, and reduces the phagocytosis of myelin by macrophages. |
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