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Name
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L-Leucine
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|---|---|
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Synonyms
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(s)-2-amino-4-methylvalericacid; 1-Leucine; 2-Amino-4-methylpentanoic acid; 2-amino-4-methylpentanoic acid; 2-amino-4-methyl-valeric acid; 4-methyl-l-norvalin; 4-methyl-norvalin; alpha-Amino-gamma-methylvaleric acid
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CAS NO
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61-90-5
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Molecular Formula
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C₆H₁₃NO₂
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Molecular Weight
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131.17
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|
EINECS
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200-522-0
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Melting Point
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>300 °C (lit.)
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|
Specific Rotation
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15.4 ° (c=4, 6N HCl)
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Boiling Point
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122-134 °C (Press: 2-3 Torr)
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Bulk Density
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300-400 kg/m³
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Density
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1.293 g/cm³
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Vapor Pressure
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<1 hPa (20 °C)
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Refractive Index
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1.4630 (estimate)
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Flash Point
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145-148 °C
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Storage Conditions
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2-8 °C
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Solubility
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Soluble in 1M HCl: 50 mg/mL
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Form
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Powder
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|
pKa
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2.328 (at 25°C)
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|
Color
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White to off-white
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|
Odor
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Odorless
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pH
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5.5-6.5 (20g/L, H₂O, 20 °C)
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|
Usage
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1. It is used in biochemical research and, in medicine, for the treatment and diagnosis of idiopathic hyperglycemia in infants, as well as for the treatment of anemia, poisoning, muscular atrophy, sequelae of poliomyelitis, neuritis, and mental illnesses.
2. It is an amino acid drug. It is used in amino acid infusions and compound amino acid preparations. Clinically, it is applied for the diagnosis and treatment of idiopathic hyperglycemia in infants, as well as for conditions such as glucose metabolism disorders, liver diseases accompanied by reduced bile secretion, anemia, poisoning, muscular atrophy, sequelae of poliomyelitis, neuritis, and mental illnesses. It is contraindicated in patients with diabetes, cerebrovascular sclerosis, and kidney diseases associated with proteinuria and hematuria. Patients with gastric and duodenal ulcers should not take this product. 3. L-leucine can be used as a nutritional supplement and a flavor enhancer. 4. It is used in the preparation of amino acid infusions and compound amino acid preparations, and also serves as a hypoglycemic agent and a plant growth promoter. 5. In accordance with China's GB 2760-96, it can be used as a fragrance. |
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