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Name
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N-Acetylneuraminic acid
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Synonyms
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5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid; LACTAMINIC ACID;
5-ACETAMIDO-3,5-DIDEOXY-D-GLYCERO-D-GALACTO-2-NONU;
5-ACETAMIDO-3,5-DIDEOXY-D-GLYCERO-D-GALACTO-2-NONULOSONIC ACID;
5-ACETAMIDO-3,5-DIDEOXY-D-GLYCERO-D-GALACTONONULOPYRANOSONIC ACID H YDRATE;
5-ACETAMIDO-3,5-DIDEOXY-D-GLYCERO-D-GALACTONONULOSONIC ACID;
5-ACETAMIDO-3,5-DI DEOXY-D-GLYCERO-D-GALACTONULOSONIC ACID;
5-ACETYLAMINO-3,5-DIDEOXY-D-GLYCERO-D-GALAC TO-2-NONULOSONIC ACID
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CAS NO
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131-48-6
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MF
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C₁₁H₁₉NO₉
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MW
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309.27
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EINECS
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205-023-1
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Melting Point
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184 - 186 °C
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Specific Optical Rotation
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-32 ° (c=2, water)
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Boiling Point
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449.56°C (rough estimate)
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Density
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1.3580 (rough estimate)
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Refractive Index
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-32 ° (C=1, H2O)
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Storage Conditions
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-20°C
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Solubility
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Solubility in water is 50 grams per liter (20°C)
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Acid Dissociation Constant (pKa)
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2.41 ± 0.54 (Predicted)
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Form
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Synthetic, crystalline
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Color
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White to off-white
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Optical Rotation
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-32
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Water Solubility
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50 g/L (20 °C)
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Stability
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Stable. Incompatible with strong oxidizing agents.
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Use
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1. Promotes Infant Brain and Nervous System Development
As an important form of sialic acid naturally present in human breast milk, N-Acetylneuraminic Acid is a key nutrient for infant brain development, neural network formation, and cognitive ability establishment. It is commonly added to premium infant formula to mimic the nutritional profile of breast milk and support early intellectual and neurological development.
2. Anti-Viral Drug Development and Immune Regulation
N-Acetylneuraminic Acid is a key receptor component that enables various viruses (such as influenza viruses) to recognize and infect host cells. It serves as the structural basis for developing anti-influenza drugs (e.g., Oseltamivir, Zanamivir) and is also widely used in immunological research and the development of immune-modulating therapeutics.
3. Applications in Functional Foods, Health Supplements, and Cosmetics
In functional foods, dietary supplements, and premium skincare products, N-Acetylneuraminic Acid is used as an active ingredient with claimed benefits for enhancing cognition, anti-aging, boosting immunity, and promoting cellular repair. It is marketed for its potential effects on improving cognitive function, providing antioxidant protection, moisturizing, and supporting skin repair, making it highly valued in the health and wellness market.
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