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Name
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L-Isoleucine
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|---|---|
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Synonyms
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(2S,3S)-2-Amino-3-methylpentanoic acid;
(2s,3s)-alpha-amino-beta-methylvaleric acid;
(2s,3s)-alpha-amino-beta-methyl-n-valeric acid;
L-Isoleucine; L-Ile;
L-Ile-OH;
L-(+)-Isoleucine, Animal-Free;
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CAS
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73-32-5
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Molecular Formula
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C6H13NO2
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Molecular Weight
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131.17
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EINECS
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200-798-2
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Melting Point
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288 °C (dec.) (lit.)
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Specific Rotation
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41 ° (c=4, 6N HCl)
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Boiling Point
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225.8±23.0 °C (Predicted)
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Bulk Density
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470 kg/m³
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Density
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1.2930 (estimate)
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FEMA
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4675
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Refractive Index
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40.5 ° (C=4, 6mol/L HCl)
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Flash Point
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168-170 °C
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Storage Conditions
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Store below +30°C.
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Solubility
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Soluble in 1M HCl: 50 mg/mL
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Form
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Powder
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Acid Dissociation Constant (pKa)
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2.32, 9.76 (at 25°C)
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Color
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White to off-white
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Odor
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Odorless
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pH
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5.5-6.5 (40g/L, H₂O, 20°C)
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Optical Rotation
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[α]20/D +41.0±1°, c = 5% in 6 M HCl
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Water Solubility
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41.2 g/L (50 °C)
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Usage
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1. Biochemical and Scientific Research Field: Used in biochemical research, bacteriological research, and tissue culture.
2. Pharmaceutical Field: Serves as a nutritional supplement, which can be used alone or in combination with other essential amino acids in amino acid preparations and amino acid infusions. 3. Food Field: Acts as a nutritional supplement to fortify foods such as wheat flour, wheat gluten, peanut flour, and potatoes (isoleucine is the limiting amino acid in these foods). The minimum daily requirement for adults is approximately 0.7g, and excessive consumption may cause an antagonistic effect with leucine, affecting growth and development. |
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