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Name
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N-Acetyl-D-Glucosamine
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|---|---|
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Synonyms
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N-Acetyl-D-glucosamine, 98.0%(LC&N);
N-acetyl-D-glucosamine;
2-Acetamido-2-deoxy-alpha-D-glucopyranose;
D-GLCNAC; ACETYL-D-GLUCOSAMINE, N-;
N-ACETYL-DELTA-GLUCOSAMINE;
2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSE,
N-ACETYL-D-GLUCOSAMINE;
2-ACETAMIDO-2-DEOXY-D-GLUCOSE
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CAS
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7512-17-6
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Molecular Formula
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C8H15NO6
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Molecular Weight
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221.21
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EINECS
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231-368-2
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Melting Point
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211 °C (dec.) (lit.)
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Specific Optical Rotation
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42 ° (c=2, water, 2 hrs)
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Vapor Pressure
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8 Pa at 20°C
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Refractive Index
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+39.0 to +42.0 (C=1, H2O)
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Storage Conditions
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-20°C
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Solubility
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Soluble in concentrated hydrochloric acid, sulfuric acid, phosphoric acid, and formic acid. Insoluble in water, dilute acid, dilute alkali, concentrated alkali, and organic solvents.
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Form
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Physiological saline suspension
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Boiling Point
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636.4±55.0 °C (Predicted)
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Density
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1.54 g/cm³
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pKa
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13.04±0.20 (Predicted)
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Color
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White to off-white
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Biological Source
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Crab (red)
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Optical Rotation
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Alpha type +75 → +41 Beta type -22 → +41.3
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Water Solubility
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H2O: 50 mg/mL colorless to faint yellow solution, clear to very slightly hazy
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Sensitivity
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Hygroscopic
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Usage
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1. It is an important precursor for the synthesis of bifidogenic factors and possesses numerous crucial physiological functions in organisms. Clinically, it is a drug for treating rheumatoid arthritis and rheumatic arthritis; it also serves as a food antioxidant, an additive in infant food, and a sweetener for diabetics.
2. It is a derivatized glucose monomer found in polymers such as bacterial cell walls, chitin, hyaluronic acid, and various glycans. D-GlcNAc is used to identify, differentiate, and characterize N-acetyl-β-D-hexosaminidase.
3. N-acetylglucosamine is a basic component unit of many important polysaccharides in biological cells, with the highest content particularly in the exoskeletons of crustaceans. It is an important precursor for the synthesis of bifidogenic factors and has many vital physiological functions in organisms.
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